<i>Escherichia coli</i> ‐associated granulomatous colitis in a cat

A six-year-old male castrated domestic shorthair cat was evaluated for a six-month history of haematochezia, mucoid diarrhoea, tenesmus and rectal prolapse. Colonic histopathology revealed multifocal mucosal ulceration lamina propria infiltration with large numbers periodic acid-Schiff-positive macrophages. Large clusters intracellular Escherichia coli were confirmed fluorescence in situ hybridization testing, similar to that seen dogs granulomatous colitis. An eight-week course marbofloxacin resulted resolution clinical signs; however, recurrence occurred four weeks later. 12-week disease remission which the still remains free signs (15 months). coli-associated colitis, although reported rarity this species, is an important infectious cause chronic intestinal cat.